The Nobel Prize in Medicine 2018 was awarded jointly to cancer researchers James P. Allison and Tasuku Honjo who discovered a cancer therapy that works by inhibition of negative immune regulation. Both researchers independently discovered methods of "removing the brakes" or stimulating the immune system to fight cancer - now called immune checkpoint therapy.
One of the proteins responsible, Programmed Death-1 (PD-1) protein, binds sialic acid confirming the critical role of carbohydrates in the fight against cancer (read more about this sialic acid binding immunoglobulin (Ig)-like lectin).
The 2018 Scientific Computing International Lecture Series (SCILS) visiting scholar will be Dr Niclas Karlsson (PI of Glyco Inflammatory Group at the University of Gothenburg, Sweden)
Dr Karlsson a Glycobioinformatician will present a departmental lecture titled "Osteoarthritis - A life science glycoproblem".
Dr Karlsson is the PI on the UniCarb-DB database that stores, integrates and processes data from manually annotated ms spectra glyco fragments.
The Scientific Computing Research Unit will be a hosting a workshop – “Molecular Dynamics using BRIDGE” at the 2018 CHPC National Conference. This will take place on the 6th December at the Century City Convention Centre. For more info see http://bit.ly/2C4ybCW. Please register online and on the CHPC registration page:
Hope to see you there! Tweet to us at @scicompute with the #bridge #galaxy #chpc2018 hashtags.
INDABA 9Sunday, 02 September 2018 - Friday, 07 September 2018
Presenting at the INDABA 9 ConferenceProf Kevin Naidoo - Multidimensional Reaction Dynamics of Enzyme Catalysis Dr Chris Barnett - Computational Cancer Glycobiology: Simulation, Analysis and Visualisation