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Nobel Prize in Medicine 2018 - cancer immunotherapy

1 Oct 2018 - 14:45

 

The Nobel Prize in Medicine 2018 was awarded jointly to cancer researchers James P. Allison and Tasuku Honjo who discovered a cancer therapy that works by inhibition of negative immune regulation. Both researchers independently discovered methods of "removing the brakes" or stimulating the immune system to fight cancer - now called immune checkpoint therapy.

One of the proteins responsible, Programmed Death-1 (PD-1) protein, binds sialic acid confirming the critical role of carbohydrates in the fight against cancer (read more about this sialic acid binding immunoglobulin (Ig)-like lectin).

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